Born in Durban, South Africa, Thero Setiloane was educated in Switzerland and the United Kingdom, where he read for a BSc in Mechanical Engineering at the University of Warwick.

Prior to joining Business Leadership South Africa (BLSA) as Chief Executive Officer in 2011, he was the Executive Vice President of Business Sustainability at AngloGold Ashanti, responsible for corporate affairs, global marketing, public policy, government relations, global security, corporate social investments, environmental and community affairs, as well as health and safety.

Thero has also held leadership positions in the telecommunications, agricultural and private equity sectors and is a graduate of the management trainee programme at Anglo American.

He is on the board of a number of companies, and previously served as a member of the Executive Committee of the World Gold Council and as an executive director of Real Africa Holdings.